Semax benefits reddit - I’ve never done this, any tips or anything I need to know? I previously thought I was a non responder to N. View community ranking In the Top 10% of largest communities on Reddit Thoughts on 7,8-Dihydroxyflavone (7,8-dhf)? I became curious about this compound because in a "what's your top nootropics" thread a pharmacologist said they have found it really interesting, not necessarily mind expanding, but having the effect of keep their mood optimistic N-Acetyl-Semax Acetate Spray emerges as a forefront solution in the realm of nootropic neuroprotective peptides, boasting an array of cognitive and physical benefits. I also think there is a wide range in strength and purity of Selank and Semax out there. The benefits can vary and I'd be writing a huge paragraph about them, I will try to keep it short and simple without omitting some key safety info. N-Acetyl Semax Amidate is usually reported to be more anxiolytic. Both Semax and Selank have been the subject of clinical trials that showcase their potent effects and benefits as nootropic peptides. something like phenylpiracetam does literally nothing for me with a stim tolerance. Most reports are from many years ago and experiences seem to be 50-50 with some people reporting no benefit and others reporting profound benefit. I would expect to some degree because semax is supposed to help heal brain injury and increase BDNF (brain derived neurotrophic factor) One thing that I think is super important is that our behavior has to be levered up particularly when we are using Semax. Both of these peptides have acute effects that are evident shortly after dosing. get reddit premium. Apr 27, 2024 · What is Semax and how is it different from Selank? Semax is a peptide distinct from Selank, known for its effects on memory formation, mood enhancement, and other cognitive functions, highlighting its differences from Selank. So will I only get the benefits for the 7 days I’m using it? Or for a prolonged period of time? From what I see people are writing that they are not consciously feeling the benefits after the discontinuing the dose. The Selank works better than any anxiety supplement or herb I have taken so I will use it again if I need too. Primarily, Semax is known to modulate the brain's dopaminergic and serotonergic systems. I added the Selank 2 weeks after I started Semax. 1% semax for a few months now and it is by FAR the most effective nootropic I use, it is a serious game changer for me, you wont need the 1% concentration. 1% for me and the wife. Get an ad-free experience with special benefits, and directly support Reddit. Amidate should be similar but last longer do you have any experience taking amphetamines? im wondering if this thing would be any good/helpful for me who has a history of adderall abuse. Benefits of Selank and Semax Selank Benefits Reduces anxiety and stress levels by stimulating GABA receptors and regulating cortisol levels[3]. So not only can Selank help relieve anxiety, but it may also provide cognitive-enhancing benefits. It's more effective and last longer. My ability to mentally "step back" and see the overall picture is increased a hundred fold. Semax altered the expression of genes that modulate the amount and mobility of immune cells and enhanced the expression of genes that encode chemokines and immunoglobulins. I (ab)used semax during a period when I had a ton of project deadlines I needed to meet, so I was both sleep-deprived and using other stimulants in conjunction with the semax. I maintain that other than RGPU-95 and Methylphenylpiracetam, which you most likely cannot acquire, nefiracetam offers the most comprehensive benefits along unique pathways. And I trialed semax, selank, bpc157, thymalin, epitalon, tb500, ipamorelin, ghk cu, KPV. I felt the benefits helping my anxiety but not enough to continue it. but i'm at the point where I know I can't really take adderall long term and it never ends well Semax affects several biological processes involved in the function of various systems. The potential applications of SEMAX paint a promising picture for those seeking to enhance cognitive prowess and safeguard neurological health. Feb 9, 2024 · Starting Semax Dose: While data on intranasal Semax is available, no published studies have examined the potential dosage of injectable Semax in clinical settings. And honestly thought I had enough info to get at least 1% tackled but Semax and Na Semax theirs so my band Im lost with this nootropic side and the brain chemistry and all that shit. There is no reason to take plain old piracetam when we have more effective alternatives, don't do it. N-Acetyl Semax and N-Acetyl Selank nasal sprays are two synthetic nootropic peptides that have been gaining popularity in recent years. Does Semax affect blood pressure? Heart rate? I have done some searching and come up empty so I thought I would post the question directly. E) Selank and Semax in the NASA form. I recall most of my moments on Semax remarkably well. I find myself able to project the future and create detailed plans for huge projects, and I also find that it gives me the mental endurance and Feb 9, 2024 · How can Semax benefits be maximized in research settings? Keep reading to discover what the latest research studies say about the benefits of Semax, including its effects on mood, cognition, and neuroprotection. Most of semax and selank reviews are people using it for mood, but what about the cognition boosting effect, what did it do for you and how effective is it, how do you compare it to other noots you tried ? From what I understand is Selank is good to take at night and Semax is good to take in the morning. For Selank the nasal way may be good but I have heard great stuff from people taking it sub cu with the more stable version N-Acetyl Selank Amidate. I kind of look at it as a "fertilizer" for my brain to grow and protect neurons. Considering switching to Reta but hear good things about semax. Apr 6, 2024 · SEMAX is theorized to modulate the expression and release of BDNF, potentially orchestrating a cascade of positive effects within the brain. My mood seemed to be better and motivation was a little higher but mostly it just kinda cleared my mind. N-acetyl is “stronger” and definitely significantly more stimulating than regular Semax. Somewhere along the way, I stumbled upon a post praising semax and its potential benefits. How many ml of BAC should I mix these 5mg with? I will inject subcutaneously. It was first developed by Soviet researchers at the Academy of Sciences of the USSR in the 1980s [1, 2, 3]. This makes it useful as part of my stack when I plan to study a subject or just when I have free time to read a ton of things of the internet. Calmed my thoughts. Selank appears to regulate critical neurotransmitters in the brain, particularly serotonin metabolism. Am i completely wrong here? We would like to show you a description here but the site won’t allow us. However, it could be what is setting off your mild asthma. Yeah it works instantly for me the key is take it sublingually. note that Semax significantly improves memory and attention, even in healthy individuals engaging in activities under extreme conditions suggests that Semax's benefits extend beyond the laboratory setting and may be applicable to real-world scenarios where cognitive performance is crucial. Here are some potential benefits of using these nasal sprays, as discussed on Reddit: Benefits of N-Acetyl Semax Amidate: Selank and Semax have been on my radar for a while but they don’t seem to be talked about much at all anymore and I’d like to hear about more recent experiences. Semax is a synthetic peptide that has gained attention for its neuroprotective properties and potential nootropic benefits. Apr 4, 2025 · Available in several forms including regular Semax, N-acetyl Semax, and N-acetyl Semax Amidate, each variant offers different levels of stability and bioavailability. Nov 3, 2021 · Read on to learn more about this drug, it’s purported effects and mechanisms, and whether its “benefits” are actually backed up by science! Disclaimer: This post is not a recommendation or endorsement for the use of Semax. Im reading things about semax and selank and kinda want to try them but i got some question first. I said this before, and I'll mention it now, there is a feeling of clearheadedness I get almost immediately after dosing. As we age our brains are slower or lose the ability of neuroplasticity. 3-1 mL twice a week[4]. That's a tough question it might alleviate some of your symptoms. Hi guys! We have had a positive feedback following our latest post on Semax, so we decided to continue the series with its smaller anxiolytic brother - Selank. Whenever I do Semax for the first time after a long break I get a great feeling for an hour or so with some other effects like better concentration and mood lift lasting a bit longer before fading into the background without much of an ending noted. It influences the levels of neurotransmitters such as dopamine and serotonin, which are crucial for mood regulation, motivation, and overall Semax is a medication which is used in Russia and Eastern Europe for the treatment of a broad range of conditions like brain trauma but predominantly for its claimed SEMAX (specifically NA SEMAX Amidate spray) increases my cognitive abilities to a point that astounds me. Whenever I conversed whilst on semax, I had my thoughts collected better and and my vocabulary seemed more extravagant. See full list on jaycampbell. so i just recently bought 10 mg Semax. Hello all, I felt compelled to write a post about the benefits of Semax and Selank, Russian peptides and nootropics, in the treatment of depression and anxiety. Semax Effects & Benefits Dec 24, 2024 · Get an ad-free experience with special benefits, and directly support Reddit. I felt the benefits of Semax before I started the selank. Nootropics join leave 419,038 readers. How much would that be in ml with BAC. I was planning on ordering some Semax 0. N-acetyl Semax is more edgy, based on most people's anecdotes. That being said, some limited research shows that Semax affects the release of certain neurotransmitters in the human brain – namely dopamine and acetylcholine – which have a significant impact on mood, learning capabilities, motivation, and attention. When off Semax I still feel all of its benefits. Semax is more powerful at increasing BDNF and NGF than noopept so I'm wondering if the sometimes reported negative effects from Noopept can also be applied to Semax. A Spectrum of Potential Benefits: Where SEMAX Shines. The FDA has not approved this drug for any specific medical or other use, and the available research on it is still Semax and or selank is next on the list for me. They are both somewhat similar, selegiline being slightly more geared to uplifting my mood and providing energy, clarity in my thoughts. They absolutely build up though, IME daily Semax was most beneficial after 2 or so weeks of it. Hair thinning/ loss can happen but is attributed to anything BDNF/NGF so not unique to Semax, and just requires lower dosing. Damn soo many want to know. Please keep us posted on how you find yourself even after stopping the semax - Its one thing for something to work but totally another to hear the benefits have remained after stopping said substance ! One of the things that Selank and Semax are supposed to help with is neuroplasticity where the brain grows and reorganizes and rewires to function in a different way. Apr 11, 2024 · Potential Benefits of Semax. I've been using 0. We will also share information on our most trusted vendors for both Semax nasal spray and subcutaneous Semax. The Semax alone was helping with the pain. Keep in mind that I cannot say if these negative side effects were directly due to the semax. Selank affects the levels of norepinephrine, dopamine metabolites, and serotonin in different brain regions in mice strains. Semax is backed up by decades of studies and clinical use as being a safe and reliable peptide, despite its mechanism of action not yet being fully understood. Semax, known for its cognitive enhancing abilities, has been linked to increased focus, memory retention, and overall mental acuity. I have heard 200mg is good. For subcutaneous injection, the suggested dosage is 0. Along with a low toxicity profile, side effects do seem relatively minimal (though a stimulant sensitivity could increase anxiety). ) If I’m being honest, they were pretty subtle. It's anxiolytic and helps me to "think better" instead of just faster or harder, the subjective effects are subtle, but the results are pretty clear. This peptide has been developed in Russia in the 1990s and has been used as a mild anxiolytic ever since. Semax offers a range of potential benefits, including improved brain health, lower stress levels, enhanced cardiovascular function, and reduced pain perception. Posted by u/Endofyouth5775 - 1 vote and no comments I'm asking because Semax and Noopept both increase BDNF and NGF, and many report these negative symptoms from Noopept usage. Does plain semax have the side effect of “Blunted Emotions” or is it just the n-Acetyl and Amidate. A Semax Amidate but responded well to regular Semax. So overall you can use them acutely or daily, both are positive IIRC 1% is generally not recommended for nootropic use, and is usually only used for medical purposes (stroke recovery for example). Selank is more sedative and Semax is a bit more of a stimulant. The semax I got from rupharma seems to be something I ingest nasally. SEMAX is an entirely different thing from modafinil for me though. If it weren't for peptides I would be suffering excruciating gut pain and anorexia, and feeling that the light or the warmth of my body and energy and spirit fades away from me slowly but faster than what a normal aging person is suffering. 2mg and was realising benefits after the first injection, but after a week of use the improvements were even more apparent. Except, if you are going through a withdrawal you won't notice all the benefits of polygala because your body is still to function without the drug. Feb 9, 2024 · What is Semax? Semax is a synthetic analog of the ACTH(4-10) fragment of adrenocorticotropic hormone (ACTH). com Sep 28, 2021 · In that bundle, you will get spray bottles of Semax Acetate, N-Acetyl Semax Acetate, and N-Acetyl Semax-Adamax Acetate. The immune response is the process most markedly affected by the drug. I decided to give it a shot and got the original Russian semax nasal drops (0. By bypassing the blood-brain barrier through perineural transport along the olfactory nerves, Semax reaches brain cells in under five minutes. Although the spikes seem to have gone now (I suspect another supplement, NA-semax-amidate; 200-300ug, typically 200ug. Again very well known, but as I N-Acetyl-Semax Acetate and N-Acetyl-Semax-Amidate Acetate are analogues of Semax. Essentially, I have found the current conversations about these two nootropics as decent at best but they miss the overall benefit of both drugs in treating mental illnesses. Semax is much more Jun 15, 2024 · Understanding the mechanism of action of Semax provides significant insights into its multifaceted benefits. Whether applying Semax, researchers are recommended to start with a lower dose ranging from 300-600mcg/daily and monitor for side effects. However, anecdotal response varies a bit from person to person. Semax delivers fast-acting results thanks to its intranasal delivery system. Tailored for individuals seeking mental acuity, neuroprotection, and overall wellness, this guide delves into the nuances of the spray and its multifaceted advantages. My buddy has tried both NA-semax and NA-semax amidate, he didn't really notice a difference IIRC. Hello dear people I have bought 5mg selank and 5mg semax. My idea is to mix 10 mg semax with 10 ml BAC water to get a 0,1 % solution. Even at 2 drops twice a day (8 drops a day between us) one bottle will only last one week. Since nootropics like Lion's Mane or Semax increase NGF and enhance neurogenesis wouldn't all the benefits be permanent since the new neurons and the enhanced cognitive abilities shouldn't go away with it ? Moreover, would taking those nootropics when the brain is still developing give even better results ? The exact dosage for Semax varies depending on the patient's response and the administration method. It's important to note that while these studies suggest that certain supplements or nutrient combinations may have potential benefits for working memory and cognitive function, more research is needed to confirm these effects and determine optimal dosages and duration of use. The cognitive benefits of Semax include enhanced focus, improved memory capacity, better problem-solving abilities, and reduced anxiety. Furthermore, Ashmarin et al. Feb 9, 2024 · Comparing Semax and Selank Benefits. TLDR; Semax changed my life, effects decreased over time but only to my benefit. Like I say my opinion and what I feel I know and get her up the info I have but I don’t know how reliable it is. With regular Semax I was taking 1. Some detail: I recently (after much consideration) ordered the Nasal version of Semax, but before it arrived I began having blood pressure spikes. It is also likely that I was using way too much semax than is recommended. Also, Semax increases immune response. May 9, 2025 · Semax's mechanism of action is still not entirely clear, as there haven't been enough studies that would explain how it works. Acetate is added to each of our peptide products for stability purposes, without acetate it would be practically impossible to store/package/ship these delicate compounds. 1%). i haven't taken aderall in weeks but i certainly have a stim tolerance. They definitely had an effect, but it is hard to describe. We would like to show you a description here but the site won’t allow us. Nevertheless, there are some differences regarding the complete spectrum of benefits that researchers may expect to observe. What are the Benefits and Effects of Semax? The main benefits and effects of Semax include: Rapid Onset and Prolonged Effects. What is the ideal dose I can't find anything useful in the German forum. I have also bought a few empty spray bottles, which i will fill with 10 ml water in order to calculate the dosage/spray, in order to know how much Semax goes into each spray. . I tried both a while ago back when ceretropic had all of their different forms (NA-selank/semax, etc. So basically, all three of the advanced versions I’ve just mentioned, only excluding the original unmodified version which you probably wouldn’t want anyway. That's good for boosting the immune system. Does plain semax work as well as some people say? Is the nasal mist the most efficient way of taking it? How about sublingually with powder form? 🙌 edit: just in case you ever delete your message, i'm copying it for the records: That had me thinking, if p21 is a good anti-agressive agent, semax is stimulating, selank is anxiolytic, and tianeptine is mood balancing and helps impulse control as my understanding of the experience reports I have read, then each serves a different purposes towards being an anti-depressant. The administration must be done correctly, by laying down with head tilted backward to ensure that fluid is absorbed in the nasal mucosa. Sep 10, 2014 · Semax is one of my favorite nootropics. N-Acetyl-Semax Spray – AMINO ASYLUM. lratnu cejnk kxrop pdnf gyylw fom urlaf qmjhrl wvgdqg jlry